AdvantiaClinical Research Centre

Current trials

Metabolic Liver Disease (MASLD/MASH)

New therapies for fatty liver disease, one of Australia's fastest-growing health issues.

Register your interest
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What is MASLD / MASH?

Metabolic dysfunction-associated steatotic liver disease (MASLD, previously known as fatty liver disease) occurs when fat builds up in the liver. In some people it progresses to MASH, where inflammation begins to damage liver cells. New medicines in clinical trials aim to reduce liver fat and inflammation before lasting damage occurs.

Common signs and symptoms

  • Often no symptoms at all (often found on blood tests or scans)
  • Fatigue
  • Discomfort in the upper right abdomen
  • Raised liver enzymes on blood tests
  • Associated type 2 diabetes or elevated cholesterol
  • Overweight or central weight gain

Could I be eligible?

You may be suitable for a current or future research study if you:

  • Are 18 years or older
  • Have been told you have fatty liver, MASLD or MASH
  • Or have risk factors such as type 2 diabetes with abnormal liver tests
  • Are interested in new treatments being studied
  • Can attend study visits in Randwick

Registering your interest does not guarantee eligibility or enrolment in a clinical trial. A member of our research team will contact you to discuss further.

Before you decide

Independently approved
Every study is reviewed and approved by an independent Human Research Ethics Committee before it opens to participants.
Entirely voluntary
You can withdraw at any time, without giving a reason, and without affecting your ongoing care.
No referral needed
You can register your interest yourself. We will let your treating doctor know only if you want us to.
Questions first, decisions later
A research coordinator talks you through what the study involves and answers your questions before you commit to anything.

Register your interest

It takes about a minute. Fields marked * are required.

Screening questions

Have you been told you have fatty liver disease (MASLD/MASH)? *

Have you had a liver scan (FibroScan or ultrasound)? *

Do you have type 2 diabetes? *

Submitting this form does not guarantee eligibility or enrolment in a clinical trial. Eligibility is determined according to the requirements of each individual research study.

Your information is secure and handled in accordance with our privacy policy.